NITROUS OXIDE - AN OVERVIEW

The final proposed mechanism of RBC vasodilation from the existence of nitrite could be the reduction of nitrite to NO by Hb. Brooks 1st studied the nitrite Hb conversation in 1937 which function was afterwards extended by Doyle in 1981 (Brooks, 1937; Doyle et al., 1981). Nitrite reacts with deoxygenated Hb to type metHb and NO (Brooks, 1937; Doyle